Hodgkin's lymphoma (Hodgkin's disease)
General description
Illustration of a lymphatic system
Parts of the immune system
Lymph nodes are grouped throughout the lymphatic system
Lymph node groups
Hodgkin's lymphoma, formerly known as "Hodgkin's disease," is a cancer of the lymphatic system, which is part of the immune system. It may affect people of any age, but it is more common in people 20 to 40 years of age and older than 55 years old.
In Hodgkin's lymphoma, the cells of the lymphatic system grow abnormally and can spread much more.
Hodgkin's lymphoma is one of the two most common types of cancer in the lymphatic system. The other type, non-Hodgkin lymphoma, is even more frequent.
Advances in the diagnosis and treatment of Hodgkin's lymphoma have helped to give people with this disease the possibility of complete recovery. The prognosis continues to improve for people with Hodgkin's lymphoma.
Hodgkin lymphoma Care at Mayo Clinic
Types
Chronic lymphocytic leukemia
Lymphoma
Cutaneous T-cell lymphoma
B-lymphocyte cutaneous lymphoma
Symptoms
swollen lymph nodes
swollen lymph nodes
Some of the signs and symptoms of Hodgkin's lymphoma are:
Painless swelling of the lymph nodes in the neck, armpits, or groin
Persistent fatigue
Fever and chills
Night Sweats
Rapid slimming without apparent cause
Itching
Increased sensitivity to the effects of alcohol or pain in lymph nodes after drinking alcohol
When to see your doctor
Ask for a doctor's visit if you have a sign or symptom that worries you.
Causes
The causes of Hodgkin's lymphoma are clear.
Doctors know that most Hodgkin's lymphomas occur when a cell which fights infections called ' B cell ' develops a mutation in its DNA. The mutation tells the cells to be rapidly dilived and to continue living when a normal cell is already dead. The mutation causes a large number of large abnormal B cells that accumulate in the lymphatic system, where they displace healthy cells and cause signeos and symptoms of Hodgkin lymphoma.
There are several types of Hodgkin lymphoma depending on the type of cells involved in the disease and its conduitea. Your type Détermina your treatment options.
Hodgkin's lymphoma, classic
Classic Hodgkin's lymphoma is the most common type of this disease. It can also be classified into sous-types. People who receive a diagnosis of classic Hodgkin lymphoma have large abnormal cells called "Reed-Sternberg cells" in the lymph nodes.
The subtypes of classical Hodgkin lymphoma include:
Hodgkin's lymphoma with Nodulaire sclerosis
Hodgkin's lymphoma with mixed cellularity
Hodgkin's lymphoma with lymphocyte depletion
Lymphocyte-rich Hodgkin lymphoma
Hodgkin's lymphoma, lymphocytic predominance
This most bizarre type of Hodgkin lymphoma involves large abnormal cells which are sometimes called ' popcorn cells ' because of their appearance. The treatment can be différent to the classic type. People with this type of Hodgkin lymphoma can l'una better cure when the disease is diagnosed with an early stage.
Risk Facteurs
Factors that increase the risk of Hodgkin's lymphoma are as follows:
Age. Hodgkin lymphoma is usually diagnosed as a personne aged between 15 and 30 years, as well as people maires of 55 years.
Antécédents Familiers of the lymphoma. Nearby a familien that has Hodgkin's lymphoma or non-Hodgkin lymphoma Incrémentala the risk of Hodgkin lymphoma.
Sex. The men fils more propense to suffer Hodgkin lymphoma.
Antérieur infection by Epstein-Barr virus. People who suffered from Epstein-Barr virus diseases, such as infectious mononucléose, are more propensity to have Hodgkin's lymphoma than people who did not have Epstein-Barr virus infections.







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